
In-Clinic Treatments
Restylane® Defyne
Restylane Defyne is a dermal filler injected under the (facial) skin. Once in place, it helps smooth away your ñlaugh linesî _ the wrinkles and folds that may form at the sides of your nose and run down toward the corners of your mouth. Restylane Defyne may also be used to improve the profile, shape, and size of your chin. Restylane Defyne is made out of hyaluronic acid - a naturally occurring sugar, found in the body that gives the skin moisture, volume, and elasticity _ and a small amount of lidocaine, which is a commonly used local anesthetic to numb the skin. The hyaluronic acid is crosslinked with BDDE, an ingredient that helps form a network of hyaluronic acid to provide a gel filler that lasts longer. Hyaluronic acid fillers, including Restylane Defyne, contain hyaluronic acid that has been modified to last longer in the body than the naturally occurring hyaluronic acid. As we age, our skin loses elasticity. This causes the lines that run along the side of the face and mouth (nasolabial folds and marionette lines) to become more pronounced as well as the chin to recede so far back toward the neck that it creates an imbalance of facial features (chin retrusion). Restylane Defyne is crafted with XpresHAn Technology to correct these deepened lines and wrinkles and improve chin projection by correcting mild-to-moderate chin retrusion. The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions„for natural-looking results that help maintain your natural movement.
Benefits
FAQs
What is Restylane Defyne for?
As you age, your facial skin begins to lose its elasticity and volume. As a result, your ñlaugh linesî, the creases that run from the sides of your nose toward the corners of your mouth, become more pronounced.
Restylane Defyne injectable gel is designed to temporarily help counter this by smoothing out these wrinkles and folds and restoring a natural, soft look to your face.
Restylane Defyne may also be used for augmentation of the chin region to improve the chin profile in patients with mild to moderate chin retrusion over the age of 21. This means it may be used in the chin area to improve the profile, shape, and size of your chin.
Restylane Defyne has been shown to maintain this effect for up to 12 months.
Are there any reasons why I should not receive Restylane Defyne?
Before using Restylane Defyne, your doctor will talk to you about your medical history, to determine if you are an appropriate candidate for treatment. You will be asked questions about possible allergies to ensure that Restylane Defyne can be safely administered. Tell your doctor about all your medical conditions, including if you:
´ Have severe allergies with a history of severe reactions (anaphylaxis). Use of Restylane Defyne may result in an allergic reaction.
´ Are allergic to the anesthetic lidocaine or to any of the proteins used to make the hyaluronic acid in Restylane Defyne (bacterial proteins). Use may result in an allergic reaction.
What side effects were seen in the clinical studies?
In the study of Restylane Defyne for correction of wrinkles and folds that form around your nose and extend down to the corners of your mouth (laugh lines), most patients reported the following side effects at the site where they received the injection:
´ Swelling
´ Lumps/Bump Formation
´ Redness
´ Pain/Tenderness
´ Bruising
´ Itching
Most patients said their side effects were mild, short-lived, and did not require them to call their doctor.
These patients said that their side effects disappeared within 1-2 weeks.
Patients also reported that the anesthetic lidocaine, which is part of the Restylane Defyne injection and used to numb the injection site, significantly reduced pain during and after their procedure.